Melatonin Market Report 2025 (Global Edition)

Global Melatonin Market Report 2025 Market Size Split by Type (Natural Melatonin, Synthetic Melatonin), by Application (Food & Beverages, Dietary Supplement, Medical, Construction, Other Applications)...

Melatonin Market Report Description

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Company Profile

Natrol, LLC

Natrol, LLC is the U.S. based manufacturer of vitamin, mineral & supplement products with numerous lines of health and wellness products including herbs and botanicals, multivitamins, specialty and sports nutrition. The company distributes its products in domestic as well as international markets. 

The company operates in over 60 countries globally. The company owns several brands including Natrol VMS, MRI, PROLAB, Laci Le Beau, Nu Hair & ShenMin and others.

RECENT NEWS

January 2022

Natrol And Jarrow Formulas came together under new company as Vytalogy Wellness
Natrol and Jarrow Formulas, two vitamin and supplement brands, officially came together as a new company, Vytalogy Wellness (Vytalogy).

Vytalogy Wellness brings together two leading vitamin and supplement brands to create products that make a transformative impact on consumers’ lives.

April 2021

Natrol launched Sleep+, a new line of melatonin products.

Natrol LLC, announced the launch of Natrol Sleep+, a line of innovative sleep aid gummies that are drug free and combine melatonin and secondary ingredients with immune health, calm, and beauty benefits, each uniquely formulated to plus up sleep.

Rexall Sundown, Inc.

Rexall Sundown, Inc. The company has segmented their products according to health interest product type, gender and format. According to health interest the products are divided into immune health, kids’ health, sleep & relaxation support, heart health, energy support, beauty and others. Further, according to product type products are divided into vitamins, minerals, multivitamins, specialty and herbs. These products are available in tablets and capsule formats.

Top Companies Market Share in Melatonin Industry: (In no particular order of Rank)

• Natrol
• Flynn Pharma Ltd.
• Fidia Farmaceutici S.P.A.
• Schiff Nutrition International Inc.
• Pharmavite
• Bebida Beverage Co.
• Nature's Bounty
• Jameison
• Rexall Sundown
• GNC
• Xiu Zheng
• Church Dwight
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*List of Second Tier Companies, List of Third Tier/ Start-up Companies (Inquire with sales executive) Request Any Company Profile for Preview Purpose OR Data Validation!

If any Company(ies) of your interest has/have not been disclosed in the above list then please let us know the same so that we will check the data availability in our database and provide you the confirmation or include it in the final deliverables.

Melatonin Market Regional Analysis

The regional analysis offers Melatonin market size, share and a detailed analysis for each region. This quantitative as well as qualitative information is crucial for new entrants along with companies operating in Melatonin market . Melatonin market production and consumption can vary significantly from one region to another owing to factors such as, the availability of raw materials, regulatory environments, and others.

The current report Scope analyzes Melatonin Market on 5 major region Split (In case you wish to acquire a specific region edition (more granular data) or any country Edition data then please write us on info@cognitivemarketresearch.com

• North America (United States, Canada, Mexico)
• Europe (United Kingdom, France, Germany, Italy, Russia, Spain, Sweden, Denmark, Switzerland, Luxembourg, Rest of Europe)
• Asia Pacific (China, Japan, South Korea, India, Australia, Singapore, Taiwan, South East Asia, Rest of APAC)
• Latin America (Brazil, Argentina, Colombia, Peru, Chile, Rest of South America)
• Middle East (Saudi Arabia, Turkey, UAE, Egypt, Qatar, Rest of Middle East)
• Africa (Nigeria, South Africa, Rest of Africa)

The above graph is for illustrative purposes only.

Melatonin Market Analysis

What is the Natural Melatonin market size?

The Natural Melatonin segment Revenue is estimated to reach USD 994.09 Million by 2028.

Natural melatonin is generated by the body. The pineal gland of mammals also produces natural melatonin. Melatonin is produced in sufficient amounts by most people's bodies to allow them to sleep. There are, however, ways to maximize the benefits of natural melatonin synthesis. Sleep aid foods, tryptophan-rich meals, vitamin B6-rich foods, avoiding screens, and relaxing in a hot bath can all help to enhance natural melatonin levels.

The advent of the COVID-19, led to the limited availability of the workers, thereby impacting the processing and development of the melatonin. The closure of the international borders is also one of the factors, leading to the disruption in the supply of several medicines, including the melatonin. The lack of transportation of raw materials and other inputs for the manufacturing and processing of melatonin supplements caused unavailability of adequate inputs. This disruption in supply chain not only hindered the manufacturing but also the supply became insufficient to match the market demand. Therefore, these are some of the factors, which are expected to hamper the growth of the melatonin market.

Synthetic Melatonin

Melatonin is most often synthesized. Synthetic melatonin is produced with yields of more than 80%, despite the presence of several by-products, i.e., undesirable substances of the chemical melatonin manufacturing methods. It is produced by four enzymatic steps from L-tryptophan, with the BH4 biosynthesis and regeneration pathways supplying the BH4 cofactor. Synthetic melatonin is safer to use since it is free of biological impurities. It is currently available in various formats such as, Immediate-release formulations, Modified release formulations, Regular, Time-release, Sublingual/transbuccal formulations, Intranasal formulations, injectable formulations, and Others.

The above Chart is for representative purposes and does not depict actual sale statistics. Access/Request the quantitative data to understand the trends and dominating segment of Melatonin Industry. Request a Free Sample PDF!

By segment, The Food & Beverages segment Revenue in Melatonin is expected to reach USD 485.97 Million by 2028.

Melatonin is often used in foods and beverages by several food and beverage firms. It has antioxidant properties, making it suitable for usage in food and beverage goods. The existence of melatonin in foods or analytical methodologies suited for testing in food matrices, as well as the possible impact of dietary consumption on human health.

Dietary Supplement

Melatonin is frequently marketed as an herbal supplement. Dietary supplements containing melatonin can be derived from animals or microbes, although they are most typically synthesized. Melatonin has been detected in a variety of foods by scientists. It is found in certain foods in higher concentrations than in others. Among plant foods, nuts, particularly pistachios, have the greatest content of melatonin. This hormone can also be found in eggs and seafood

Medical

Melatonin is a hormone that has been used in alternative medicine to cure insomnia (trouble falling asleep or staying asleep). It is also considered to be useful in the treatment of sleep disturbances in blind persons. Melatonin is also used to treat infertility, ease sleep issues caused by shift work, and boost sports performance

Construction

For the construction and insulation of buildings, Melatonin is employed in bio-based spray polyurethane foam manufacture. Spray polyurethane foam (SPF) has been utilized by building owners as roofing, insulation, and sealing material.

Other

Melatonin is extremely lipophilic (fat-soluble) and water-loving, allowing it to easily permeate skin cells and perform key physiological processes including mitochondrial and DNA repair. Melatonin is therefore utilized in cosmetics. Melatonin is often advised as part of a skincare program.

The above Graph is for representation purposes only. This chart does not depict actual Market share.

Melatonin Shapes Segment Analysis

• Pills
• Liquids
• Chewable

Melatonin Treatments Segment Analysis

• Medicinal
• Preventive

The base years considered for all the estimations by analyzing trends and growth rate will help you gain an in-depth understanding of the conclusions provided in this report. This report also includes figures, graphs, pie charts, tables and bar graphs that explain the data analysis based on current trends at the country level as well as key regions. This research report also focuses on assessing factors such as profit, product price, capacity, production, supply demand market growth rate along with others to create a clear picture on the future prospects of this market.

Author's Detail

Ashwini Moharir

Research Analyst at Cognitive Market Research

LinkedIn

Profile

Enthusiastic and analytical market research professional with 2 years of hands-on experience in tracking market trends, evaluating consumer behavior, and supporting strategic decision-making. Proficient in designing surveys, conducting interviews, and synthesizing insights from both primary and secondary sources. Successfully contributed to research projects across sectors such as retail, personal care, and industrial markets. Brings a keen eye for detail, strong data interpretation skills, and a passion for uncovering what drives markets forward. Comfortable working in fast-paced environments and collaborating across departments to deliver clear, actionable findings.

Author's Conclusion