Diabetic Foot Ulcers Treatment Market Report 2025 (Global Edition)

Current scenario of the diabetic foot ulcer treatment market 

Key opportunity in the diabetic foot ulcer treatment market

• Growing technological advancement is driving the diabetic foot ulcer treatment market.

High blood sugar levels brought on by diabetes can cause several complications, including dementia, cardiovascular disease, eye, kidney, and nerve damage (retinopathy), as well as hearing loss and delayed wound healing—one of the most dangerous effects of the disease. For severe diabetic wounds, amputation may be necessary. Patients with diabetes are at risk for infection because their wounds heal more slowly and incompletely. Clinical trials are using the most recent developments in hydrogels, nanoparticles, and nanotechnology to help diabetic people or animal models heal their wounds more quickly. By combining non-bioactive materials (metal ions, nitric oxide, etc.) with bioactive molecules, these hydrogels/nanoparticles facilitate the healing of diabetic wounds. These days, smart hydrogels are preferred by researchers. 

For example,
The nanofiber scaffold is designed to release peptide molecules that accelerate wound healing, which was confirmed by in vitro and in vivo studies. The peptide-loaded nanofiber samples showed better adhesion, proliferation, migration, and fibroblast cell growth than other groups. In vivo studies in a mouse model demonstrated that the designed nanofiber was gradually absorbed without causing dryness or infection, and it showed excellent tissue repair ability. Gene expression studies indicate that the antimicrobial peptide promotes the inflammatory phase of wound healing in a shorter time frame by accelerating the tumor necrosis factor-α cytokine response.

Source (https://www.degruyter.com/document/doi/10.1515/ntrev-2023-0129/html?lang=en#:~:text=The%20nanofiber%20scaffold%20is%20designed,cell%20growth%20than%20other%20groups.) 

Furthermore, diabetic wound repair can be treated with hydrogels and nanoparticles in conjunction with specific technologies (such as 3D printing and self-assembly technology). Topical insulin has gained favor as a healing agent for diabetic foot ulcers. However, because of the fragility of the molecule, topical insulin presents a substantial barrier. Insulin is added to hydrogels to optimize its effects and guarantee molecular stability. Lately, hydrogels containing drugs and cells have demonstrated encouraging outcomes in the healing of wounds. 

For example,
Hydrogel stem cell therapy can promote wound healing by secreting cell growth factors and exosomes and cooperating with drugs. Chronic wounds are characterized by unbalanced inflammatory responses, oxidative stress effects, hyperglycemia, absence of angiogenesis, and a high risk of bacterial infection. Hydrogel-based stem cell therapy has gained attention for diabetic wound healing due to its water absorption, permeability, biocompatibility, and drug-loading ability. Several hydrogels have been developed for diabetic wound healing, such as chitosan polyurethane hydrogel membrane (HPUC), self-healing hydrogel containing 2×105 BMSCs, and self-healing hydrogels containing 2×105 BMSCs. Clinical studies have shown that hydrogel-based allogeneic ADSCs sheets can promote wound closure without adverse effects within 12 weeks. An injectable hydrogel loaded with umbilical cord stem cell factor has been developed for diabetic rat wound treatment.

Source (https://www.frontiersin.org/articles/10.3389/fchem.2022.1038839/full) 

Consequently, there will probably be a surge in demand for efficient diabetic wound infection treatments shortly on a global scale.

Key drivers of the Diabetic Foot ulcer treatment market

• Increasing prevalence of diabetic foot ulcer to drive diabetic foot ulcer treatment market growth

A diabetic foot ulcer is one of the most significant and devastating complications of diabetes. Along with the rising prevalence of diabetes, an increase in its complications is witnessed. Various factors such as advancing age, sedentary lifestyle, and longer duration of diabetes mellitus have been responsible for increasing the prevalence of these ulcers. 

For example,
About one-third of people with diabetes develop a foot ulcer during their lifetime. Diabetic foot ulcers affect about 18.6 million people worldwide and 1.6 million in the US annually. Approximately half of diabetic foot ulcers become infected, and about 20% of these infections result in amputation of part of the foot or the whole foot.

Source (https://jamanetwork.com/journals/jama/fullarticle/2812203#:~:text=About%20one%2Dthird%20of%20people,million%20in%20the%20US%20annually.) 

Diabetes foot is one of the most serious complications of diabetes. It is the primary cause of hospital admissions, amputations, and deaths in diabetic patients. The risk of death in the diabetic population with foot ulcers is 2.5 times higher than that of those without ulcers. Diabetic foot complications result in a significant clinical and financial burden. The risk of complications increases with poor glycemic control, smoking, foot deformities, peripheral neuropathy, visual loss, and chronic kidney diseases

This, along with the increasing awareness about the availability of treatment and the rise in healthcare expenditure among the patient population, especially in emerging countries is anticipated to further augment the market during the forecast period.

• The growing geriatric population drives the diabetic foot ulcer treatment market growth.

The aging population is the primary driver of the diabetic foot ulcer treatment market's expansion. Another factor propelling the diabetic foot ulcer treatment market is the aging population. As people age, they become more susceptible to chronic illnesses including diabetes, peripheral neuropathy, and peripheral artery disease, all of which raise the risk of foot ulcers. The need for innovative diabetic foot ulcer treatments is driven by the increasing number of elderly individuals. 

For example,
According to the WHO, chronic conditions, such as diabetes, are highly prevalent in older people aged 65 years and above. The population is aging at a considerably higher rate than in the past. In 2020, the number of people aged 60 years and older will outnumber children aged under five years.

Source (https://www.who.int/news-room/fact-sheets/detail/ageing-and-health) 

Moreover, a rise in the geriatric population in Asia Pacific, especially in countries with untapped opportunities, such as Japan, India, and China, is expected to drive growth. Therefore, with the increase in the aging population, the demand for short- and long-term healthcare needs is also increasing, which is expected to drive industry growth.

Key restraints of the Diabetic Foot ulcer treatment market

• The increasing cost of treatment hampers the Diabetic Foot ulcer treatment market growth.

The high cost of the treatment could impede the growth of the diabetic ulcer treatment market. Diabetes ulcers frequently call for specialized, long-term care from a variety of medical specialists, including endocrinologists, podiatrists, and wound care specialists. In addition, antimicrobial dressings, bandages, antibiotics, topical ointments, and diabetic-specific footwear must be changed regularly for these ulcers. The price of these supplies raises the total cost even further. 

Additionally, several diagnostics, including blood tests, MRIs, X-rays, and Doppler ultrasounds, are necessary for the accurate diagnosis and ongoing monitoring of diabetic ulcers. Surgical procedures like debridement or skin grafts could be required in extreme situations. These are costly treatments that can add a substantial amount to the entire cost of treatment.

How did COVID-19 impact the Diabetic Foot ulcer treatment market?

The coronavirus pandemic is expected to have a major impact on a certain medical equipment segment since non-emergency procedures and healthcare services are slowing down. To lower the danger of virus infection, the American College of Surgeons, the Centers for Medicare and Medicaid Services (CMS), and the U.S. Surgeon General all advised postponing or canceling non-essential medical and surgical procedures in March 2020. In light of this, numerous nations have shifted healthcare resources for the care of COVID-19 patients, including hospital beds, nurses, key professionals, and medical equipment. As a result, wound care treatments are now temporarily removed from the list of necessary operations. It's critical to recognize that this kind of foot ulcer does not pose a threat to one's limb and to plan for at-home or telemedicine treatment. This has had a major effect on the number of patients visiting outpatient clinics and wound care centers, particularly in the United States and Europe. In light of the current COVID-19 pandemic, open wound treatment centers with full staffing are reporting a forty percent decrease in patient volume. Consequently, the market has suffered due to the COVID-19 pandemic. The COVID-19 pandemic, however, had a detrimental effect on the worldwide market for diabetic foot ulcer treatment since it reduced the number of beds and operating rooms available, which further caused significant delays in urgent and semi-elective surgical procedures. As most elective and non-urgent cases were postponed during the COVID-19 pandemic, the nature of surgery and anesthesia techniques changed, according to an American College of Surgeons (ACS) 2021 report.

Our study will explain complete manufacturing process along with major raw materials required to manufacture end-product. This report helps to make effective decisions determining product position and will assist you to understand opportunities and threats around the globe.

The Global Diabetic Foot Ulcers Treatment Market is witnessing significant growth in the near future.

In 2023, the Wound Care Dressings segment accounted for noticeable share of global Diabetic Foot Ulcers Treatment Market and is projected to experience significant growth in the near future.

The Hospitals segment is expected to expand at the significant CAGR retaining position throughout the forecast period.

Some of the key companies ConvaTec , Acelity L.P. and others are focusing on its strategy building model to strengthen its product portfolio and expand its business in the global market.

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