Global API Intermediate
Market Report
2025
Delivery Includes:- Market Timeline 2021 till 2033, Market Size, Revenue/Volume Share, Forecast and CAGR, Competitor Analysis, Regional Analysis, Country Analysis, Segment Analysis, Market Trends, Drivers, Opportunities, Restraints, ESG Analysis, Porters Analysis, PESTEL Analysis, Market Attractiveness, Patent Analysis, Technological Trend, SWOT Analysis, COVID-19 Analysis, Consumer Behavior Analysis, etc.
The base year for the calculation is 2024. The historical will be 2021 to 2024. The year 2025 will be estimated one while the forecasted data will be from year 2025 to 2033. When we deliver the report that time we updated report data till the purchase date.
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According to Cognitive Market Research, the Global API intermediate Market Size will be USD XX Billion in 2023 and is set to achieve a market size of USD XX Billion by the end of 2031 growing at a CAGR of XX% from 2024 to 2031.
• The global APIs intermediate market will expand significantly by XX% CAGR between 2024 and 2031.
• The bulk drug type segment accounts for the largest market share and is anticipated to a healthy growth over the approaching years.
• The CMO segment by end user holds the largest share and is expected to grow in the coming years as well.
• cardiology application is the market's largest contributor and is anticipated to expand at a CAGR of XX% during the projected period.
• The sector has seen a transformation in indirect sales with the rise of e-commerce and online marketplaces
• Asia Pacific region dominated the market and accounted for the highest revenue of XX% in 2022 and it is projected that it will grow at a CAGR of XX% in the future.
2021 | 2025 | 2033 | CAGR | |
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Global Market Size | 121212 | 121212 | 121212 | 121212 |
Country Market Size | 121212 | 121212 | 121212 | 121212 |
North Americ Market Size | 121212 | 121212 | 121212 | 121212 |
Europe Market Size | 121212 | 121212 | 121212 | 121212 |
Asia Pacific Market Size | 121212 | 121212 | 121212 | 121212 |
South America Market Size | 121212 | 121212 | 121212 | 121212 |
Middle East Market Size | 121212 | 121212 | 121212 | 121212 |
Africa Market Size | 121212 | 121212 | 121212 | 121212 |
Base Year | 2024 |
Historical Data Time Period | 2021-2024 |
Forecast Period | 2025-2033 |
Market Split by Type |
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Market Split by Application |
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Market Split by End User |
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Market Split by Conclusion | |
List of Competitors |
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Regional Analysis |
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Country Analysis |
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Market Drivers:
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Market Restrains:
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Market Trends:
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Report scope is customizable as we have a huge database of API Intermediate industry. We can deliver an exclusive report Edition/Consultation as per your data requirements. Request for your Free Sample Pages.
API Intermediate Market is Segmented as below. Particular segment of your interest can be provided without any additional cost. Download the Sample Pages!
An API intermediate or active pharmaceutical ingredient is a chemically active substance that is responsible for the intended pharmacological activity of a medication. The role of API intermediates in pharmaceutical products is crucial. The introduction of new and advanced technologies for API manufacturing is one of the major factors supporting the growth of this market. APIs have been pivotal in the development of pharmaceuticals to combat a wide range of communicable diseases, including viral and bacterial infections.
Additionally, Demand for APIs is influenced by a variety of factors, including overall pharmaceutical industry growth, product demand for therapeutic areas, and financing trends, particularly for smaller pharmaceutical companies, noted Kate Kuhrt, head of Go-to-Market for the Life Sciences business at Clarivate Analytics, a provider of insights and analytics. for instance- On a therapeutic basis, oncology/immuno-modulators represent the leading class both in terms of global new product launches and R&D spending. (source:https://www.chemanager-online.com/en/news/apis-evaluating-supply-and-demand. )Hence, the market growth for API intermediate will increase by XX% CAGR over the expected period.
The rising prevalence of chronic disease is expected to increase the need for pharmaceutical treatments, propelling the market's growth for active pharmaceutical components over the forecast period. In addition, some of the strategic measures being undertaken to maintain market stability include the introduction of new pharmaceuticals and biological products, partnerships, acquisitions, and regional expansions.
For instance- According to WHO, cardiovascular diseases cause the death of 17.9 million people per day and are expected to cause approximately 25 million deaths by 2030. Increasing epidemiology of lifestyle, aided by the rising number of smokers globally, growing incidence of obesity, and increasing dietary irregularities, are factors likely responsible for propelling market growth. (source:https://www.contractpharma.com/contents/view_online-exclusives/2024-01-25/api-market-trends/)
Furthermore, advancements in medical technology, an increase in the number of initiatives launched by public and private organizations to raise awareness, and an increase in government funding will all contribute to the growth of the active pharmaceutical ingredient (API) market. The market for active pharmaceutical ingredients (API) will also increase as disposable income levels grow.
An escalating global chronic disease burden drives pharmaceutical production, increasing the need for APIs. Generic drugs, equivalent in efficacy to brand-name counterparts but cost-effective, witness high demand, particularly in the treatment of chronic ailments. The rise in age-related health issues contributes to elevating the demand for pharmaceuticals, influencing API market growth.
Additionally, as biopharmaceuticals such as recombinant proteins and monoclonal antibodies have grown in popularity, so has the demand for bioprocess intermediates. These phases in the process are required to generate biologics, which is fueling industry growth. Hence the market of active pharmaceutical ingredients (API) is growing because of the rising demand for generics and therapeutics usage.
According to the World Health Organization (WHO), 10.5% of the world's medicines are counterfeits (substandard or falsified) reaching up to 50% of the supply in developing countries (World Health Organization). The availability of substandard and counterfeit drugs is expected to hinder the market’s growth over the forecast period. Also, Hazardous substances and reactions can be used in the chemical synthesis process. Counterfeit medicines are harmful to health because they generally: Contain incorrect amounts of APIs (or are missing APIs) and Contain dangerous substitutes, contaminants, and other toxic components instead of quality-controlled formulas and approved API percentages.
Active Pharmaceutical ingredient is a crucial part of any drug product that can directly influence the safety and efficacy of the medicinal product which may endanger the life of the patient. ‘API’ takes into consideration the regulatory requirements associated with it in 3 different countries USA, India, and Europe to check the quality control parameters.
Additionally, despite high manufacturing expenses, strict regulatory policies, and policies in controlling drug prices in many countries, attractive opportunities have emerged in the API market due to growing cases of chronic diseases, including diabetes, asthma, and cancer. For instance- “Any supplier of APIs, packaging materials, or services has the competence to consistently meet previously established requirements,” APIC adds. Independent quality units’ roles within this framework should also be put down in the form of a contract or agreement. The committee also recommends the establishment of an independent quality unit to oversee quality assurance (QA) tasks such as documentation and traceability of API distribution activities. (source:https://medwinpublishers.com/PDRAJ/active-pharmaceutical-ingredients-api-regulations-in-india-usa-and-europe-a-comparative-study.pdf)
With the increase in research and development activities, public and private organizations are creating new chances for market growth. Collaboration among API intermediate producers, pharmaceutical companies, and research organizations can lead to innovative solutions and access to new markets.
For instance- CytoReason announced an extension of its multi-year partnership with Pfizer to use CytoReason’s artificial intelligence technology for Pfizer’s drug development programs. (source:https://www.pfizer.com/news/press-release/press-release-detail/cytoreason-announces-expanded-collaboration-deal-pfizer)
This partnership is advancing a significant shift in the biotech industry, and helping drive future R&D for pharmaceutical companies as they continue to use machine learning to develop treatments more efficiently. Transforming complex data into useful actionable insights will potentially provide leading researchers and scientists a roadmap to further develop their drug portfolios.”
• 28 June 2023, GSK plc announced the acquisition of BELLUS Health Inc., a biopharmaceutical company. The acquisition is focused on developing therapy for refractory chronic cough (RCC).
• In January 2023, Sai Life Sciences announced the launch of a new high-potency API (HPAPI) manufacturing facility at its cGMP API manufacturing site in Bidar, India. This new facility broadens the company's expertise in HPAPI development and manufacturing.
• In January 2023, Agilent Technologies Inc. announced an investment of around $725 million to double the manufacturing capacity of therapeutic nucleic acids in response to a strong demand for the company’s API.
• On 5 January 2023, the U.K. government signed a memorandum of understanding with BioNTech aimed at accelerating clinical trials for personalized immunotherapies for cancer and infectious disease vaccines.
The API intermediate Market has experienced significant impacts as a result of the COVID-19 pandemic. The COVID-19 pandemic has caused an intolerable impact on the health structure as well as the pharmaceutical sector, which in ultimatum has created enormous issues in the everyday lives of the patient community. The pandemic led to a lot of disruptions and commotions in the supply chains leading to postponements and delays in the manufacturing and distribution of the systems. Different disturbances like worldwide lockdowns, closing down factories, and restrictions on transportation impacted the availability of raw materials and types of equipment.
For instance- Among the problems for pharmaceutical supply chains during this pandemic are the restrictions and impact of COVID-19 on two of the largest global producers of active pharmaceutical ingredients (APIs) and generics: China and India. (source:https://www.europeanpharmaceuticalreview.com/article/116145/covid-19-update-coronavirus-and-the-pharmaceutical-supply-chain/)
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The reintroduction of tariffs under President Trump’s “Liberation Day Tariffs” in April 2025 has created significant disruption in global pharmaceutical trade. These tariffs, ranging from 10% to 46%, specifically target pharmaceutical products, APIs (active pharmaceutical ingredients), medical packaging, and machinery from key manufacturers in China and India. This has led to increased production costs, supply chain delays, and regulatory challenges for U.S.-based pharmaceutical companies.
The tariffs have particularly impacted generic drug manufacturers, who rely heavily on APIs from China and India. Biopharmaceuticals and vaccines are also feeling the pressure, with tariffs on critical materials like bioproduction media and cold-chain packaging raising costs by up to 25%. Similarly, contract manufacturing organizations (CMOs) are grappling with the need to identify new suppliers and adjust production plans to mitigate rising costs.
Foreign governments, including the European Union, have retaliated with tariffs on U.S. pharmaceutical exports, further complicating global trade. Clinical trials are also impacted, as tariffs on drugs and diagnostic kits delay trial timelines.
Market research is increasingly crucial for navigating these challenges. By providing real-time data on API pricing, supplier reliability, and tariff impact, pharmaceutical firms can make informed decisions on sourcing, compliance, and investment strategies. This data-driven approach helps mitigate risks, optimize supply chains, and identify alternative manufacturing hubs to offset tariff-related disruptions.
Overall, market research is essential for pharmaceutical companies to adapt to the new tariff landscape, enabling them to maintain competitive advantage and navigate global trade dynamics effectively.
The API intermediates market competitive landscape provides a detailed analysis of competitors. The detailed analysis includes company overview, company financial statements, revenue generated, market potential, investment in research and development, new market initiatives, regional presence, company strengths and weaknesses, product launch, product width and breadth, and application dominance
Top Companies Market Share in API Intermediate Industry: (In no particular order of Rank)
If any Company(ies) of your interest has/have not been disclosed in the above list then please let us know the same so that we will check the data availability in our database and provide you the confirmation or include it in the final deliverables.
According to Cognitive Research, the Asia Pacific region dominated the market and accounted for the highest revenue of XX% in 2022 and it is projected that it will grow at a CAGR of XX% in the future. The regional market is anticipated to be driven by factors such as an enhanced regulatory framework, substantial opportunities for cost saving, heightened complexity, and a robust drug pipeline. Countries like India and China are the largest manufacturers of APIs globally, primarily due to the high pharmaceutical R&D investment across Asian countries.
North America is projected to grow at a CAGR of XX% over the period. The rise in the generic population leads to more chronic diseases such as cardiac diseases, orthopaedic diseases, respiratory diseases, and others. Hence, increases the demand for drugs and API intermediates, thus boosting the market growth.
The current report Scope analyzes API Intermediate Market on 5 major region Split (In case you wish to acquire a specific region edition (more granular data) or any country Edition data then please write us on info@cognitivemarketresearch.com
The above graph is for illustrative purposes only.
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According to Cognitive Market Research, the North America API intermediate Market Size will be USD XX Billion in 2023 and is set to achieve a market size of USD XX Billion by the end of 2031 growing at a CAGR of XX% from 2024 to 2031.
According to Cognitive Market Research, the Europe API intermediate Market Size will be USD XX Billion in 2023 and is set to achieve a market size of USD XX Billion by the end of 2031 growing at a CAGR of XX% from 2024 to 2031.
According to Cognitive Market Research, the Asia Pacific API intermediate Market Size will be USD XX Billion in 2023 and is set to achieve a market size of USD XX Billion by the end of 2031 growing at a CAGR of XX% from 2024 to 2031.
According to Cognitive Market Research, the South America API intermediate Market Size will be USD XX Billion in 2023 and is set to achieve a market size of USD XX Billion by the end of 2031 growing at a CAGR of XX% from 2024 to 2031.
According to Cognitive Market Research, the Middle East and Africa API intermediate Market Size will be USD XX Billion in 2023 and is set to achieve a market size of USD XX Billion by the end of 2031 growing at a CAGR of XX% from 2024 to 2031.
Global API Intermediate Market Report 2025 Edition talks about crucial market insights with the help of segments and sub-segments analysis. In this section, we reveal an in-depth analysis of the key factors influencing API Intermediate Industry growth. API Intermediate market has been segmented with the help of its Type, Application End User, and others. API Intermediate market analysis helps to understand key industry segments, and their global, regional, and country-level insights. Furthermore, this analysis also provides information pertaining to segments that are going to be most lucrative in the near future and their expected growth rate and future market opportunities. The report also provides detailed insights into factors responsible for the positive or negative growth of each industry segment.
Based on type, the bulk drug segment dominates the market of API intermediates among others. The bulk drug intermediates segment had the largest revenue share in the market. The bulk drug intermediates sector is expected to dominate the market due to the increasing prevalence of chronic disease and the development of market participants producing bulk drug intermediates. Active pharmaceutical ingredients (API) are routinely manufactured from bulk drug intermediates. The active pharmaceutical ingredient (API) is a necessary component used in the manufacture of pharmaceuticals to provide the intended therapeutic effect.
Fine chemicals, on the other hand, are produced by a limited number of companies. The developing and manufacturing process of fine chemicals is complex and usually subject to multi-step synthesis. Also They are also much more expensive to produce than bulk chemicals, due to their complexity and changing chemistries.
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Senior Research Associate at Cognitive Market Research
Manjiri Kanhere is an experienced market researcher focused on the Pharma & Healthcare industry. With over 3+ years of experience, She has worked with major pharmaceutical companies and healthcare providers, helping them to understand market trends, identify new business opportunities, and develop effective sales & marketing strategies. Her expertise lies in the ability to analyze complex data sets and deliver insights that drive business decisions. At Cognitive Market Research, she handles the market research related to Pharma and healthcare industry.
Manjiri Kanhere is an experienced market researcher focused on the Pharma & Healthcare industry. With over three years of experience, She has worked with major pharmaceutical companies and healthcare providers, helping them to understand market trends, identify new business opportunities, and develop effective sales & marketing strategies.
In her current role, Manjiri handles the market research related to Pharma and healthcare industry. Her passion lies in utilizing innovative approaches to distill complex information into strategic insights that empower organizations to make informed decisions.Manjiri remains an invaluable asset in the dynamic landscape of market research.
With the help of the above study about the API intermediate market, it can be concluded that the market for API intermediate worldwide is expected to develop significantly soon. From the report, one can understand and infer the market dynamics, segmentations, status and trends, and key players in the market. It provides data regarding various topics such as market dimensions, prevailing trends, competitive landscape, and the outlook for prospective expansion. This allows the reader to understand and access reliable data about the market and industry.
Please note, we have not disclose, all the sources consulted/referred during a market study due to confidentiality and paid service concern. However, rest assured that upon purchasing the service or paid report version, we will release the comprehensive list of sources along with the complete report and we also provide the data support where you can intract with the team of analysts who worked on the report.
Disclaimer:
Type | Bulk Drug Intermediates, Chemical Intermediates |
Application | Analgesics, Anti-Infective Drugs, Antidiabetic Drugs, Cardiovascular Drugs, Anticancer Drugs, Others |
End User | Biotech and Pharmaceutical Companies, CMO, Others |
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List of Competitors | BASF, Jigs Chemical, Sanofi Winthrop, Ami, Cambrex, A.R.Life Sciences, Dragon Hwa, Shandong Jiulong, Hipharma, AMPAC, Sandoo Pharmaceuticals and Chemicals Co., Ltd., Cipla limited. |
This chapter will help you gain GLOBAL Market Analysis of API Intermediate. Further deep in this chapter, you will be able to review Global API Intermediate Market Split by various segments and Geographical Split.
Chapter 1 Global Market Analysis
Global Market has been segmented on the basis 5 major regions such as North America, Europe, Asia-Pacific, Middle East & Africa, and Latin America.
You can purchase only the Executive Summary of Global Market (2019 vs 2024 vs 2031)
Global Market Dynamics, Trends, Drivers, Restraints, Opportunities, Only Pointers will be deliverable
This chapter will help you gain North America Market Analysis of API Intermediate. Further deep in this chapter, you will be able to review North America API Intermediate Market Split by various segments and Country Split.
Chapter 2 North America Market Analysis
This chapter will help you gain Europe Market Analysis of API Intermediate. Further deep in this chapter, you will be able to review Europe API Intermediate Market Split by various segments and Country Split.
Chapter 3 Europe Market Analysis
This chapter will help you gain Asia Pacific Market Analysis of API Intermediate. Further deep in this chapter, you will be able to review Asia Pacific API Intermediate Market Split by various segments and Country Split.
Chapter 4 Asia Pacific Market Analysis
This chapter will help you gain South America Market Analysis of API Intermediate. Further deep in this chapter, you will be able to review South America API Intermediate Market Split by various segments and Country Split.
Chapter 5 South America Market Analysis
This chapter will help you gain Middle East Market Analysis of API Intermediate. Further deep in this chapter, you will be able to review Middle East API Intermediate Market Split by various segments and Country Split.
Chapter 6 Middle East Market Analysis
This chapter will help you gain Middle East Market Analysis of API Intermediate. Further deep in this chapter, you will be able to review Middle East API Intermediate Market Split by various segments and Country Split.
Chapter 7 Africa Market Analysis
This chapter provides an in-depth analysis of the market share among key competitors of API Intermediate. The analysis highlights each competitor's position in the market, growth trends, and financial performance, offering insights into competitive dynamics, and emerging players.
Chapter 8 Competitor Analysis (Subject to Data Availability (Private Players))
(Subject to Data Availability (Private Players))
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
This chapter would comprehensively cover market drivers, trends, restraints, opportunities, and various in-depth analyses like industrial chain, PESTEL, Porter’s Five Forces, and ESG, among others. It would also include product life cycle, technological advancements, and patent insights.
Chapter 9 Qualitative Analysis (Subject to Data Availability)
Segmentation Type Analysis 2019 -2031, will provide market size split by Type. This Information is provided at Global Level, Regional Level and Top Countries Level The report with the segmentation perspective mentioned under this chapters will be delivered to you On Demand. So please let us know if you would like to receive this additional data as well. No additional cost will be applicable for the same.
Chapter 10 Market Split by Type Analysis 2021 - 2033
The report with the segmentation perspective mentioned under this chapters will be delivered to you On Demand. So please let us know if you would like to receive this additional data as well. No additional cost will be applicable for the same.
Chapter 11 Market Split by Application Analysis 2021 - 2033
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Chapter 12 Market Split by End User Analysis 2021 - 2033
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Chapter 13 Market Split by Conclusion Analysis 2021 - 2033
This chapter helps you understand the Key Takeaways and Analyst Point of View of the global API Intermediate market
Chapter 14 Research Findings
Here the analyst will summarize the content of entire report and will share his view point on the current industry scenario and how the market is expected to perform in the near future. The points shared by the analyst are based on his/her detailed in-depth understanding of the market during the course of this report study. You will be provided exclusive rights to interact with the concerned analyst for unlimited time pre purchase as well as post purchase of the report.
Chapter 15 Research Methodology and Sources
Why Bulk Drug Intermediates have a significant impact on API Intermediate market? |
What are the key factors affecting the Bulk Drug Intermediates and Chemical Intermediates of API Intermediate Market? |
What is the CAGR/Growth Rate of Analgesics during the forecast period? |
By type, which segment accounted for largest share of the global API Intermediate Market? |
Which region is expected to dominate the global API Intermediate Market within the forecast period? |
Segmentation Level Customization |
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Region level Data Customization |
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Country level Data Customization |
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Company Level |
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Additional Data Analysis |
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Additional Qualitative Data |
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Additional Quantitative Data |
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Service Level Customization |
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Report Format Alteration |
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